Description

(2R,3R,10S,12S,13R,14R,17R)-17-[(2R,5R)-5,6-dihydroxy-6-methyl-heptan-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-2,3,12-triol is a high-purity, complex steroidal diol derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral intermediate or reference standard for synthesizing novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel steroidal drugs and hormone analogs.
• Biochemical Research: Reference standard and probe compound for studying steroid receptor interactions and metabolic pathways.
• Process Development: Used in route scouting and optimization for the commercial-scale production of complex active pharmaceutical ingredients (APIs).
• Analytical Standard: High-purity material for method development, validation, and quality control in analytical laboratories (HPLC, LC-MS).
• Academic Research: Tool for investigating stereoselective synthesis and the structure-activity relationships (SAR) of polyhydroxylated steroids.

Basic Information

Product Name	(2R,3R,10S,12S,13R,14R,17R)-17-[(2R,5R)-5,6-dihydroxy-6-methyl-heptan-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-2,3,12-triol
CAS No.	64971-22-8
Molecular Formula	C30H50O5
Molecular Weight	490.72 g/mol
Synonyms	4,4,10,13,14-Pentamethyl-17-[(2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-2,3,12-triol; (22R)-Ergosta-5,7,22-trien-3β-ol trihydroxy derivative; Polyhydroxylated sterol derivative; Steroidal pentol intermediate; CAS 64971-22-8.
EINECS	Contact for details

Quality Control

Our (2R,3R,10S,12S,13R,14R,17R)-17-[(2R,5R)-5,6-dihydroxy-6-methyl-heptan-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-2,3,12-triol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, documenting results for chiral purity, chemical assay, and related substances. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.