Description

[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl [[4-[[3-(2-hexadecanoylsulfanylethylamino)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-oxidophosphoryl] phosphate is a complex, high-purity nucleotide-lipid conjugate designed for advanced biochemical and pharmaceutical research. This compound matters as a critical building block for developing novel drug delivery systems, particularly in the formulation of liposomal and nanoparticle-based therapeutics. It is essential for researchers and manufacturers in the fields of nucleic acid delivery, vaccine development, and targeted cancer therapy who require specialized, high-quality chemical intermediates.

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic lipid component for constructing stable, ionizable cationic lipid systems used in mRNA vaccine and therapeutic delivery.
• Advanced Drug Delivery Research: Serves as a functionalized lipid conjugate for creating targeted delivery vehicles for oligonucleotides, siRNA, and other nucleic acid-based drugs.
• Bioconjugation and Probe Development: Used in the synthesis of labeled nucleotide analogs for diagnostic assays, imaging probes, and cellular uptake studies.
• Pharmaceutical Intermediate: A critical raw material in the synthesis pathway of next-generation antiviral and anticancer prodrugs.
• Biochemical Tool Compound: Employed in academic and industrial research to study membrane interactions, intracellular trafficking, and nucleotide metabolism.

Basic Information

Item	Detail
Product Name	[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methyl [[4-[[3-(2-hexadecanoylsulfanylethylamino)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]-oxidophosphoryl] phosphate
CAS No.	62358-02-5
Molecular Formula	C39H65N8O17P3S
Molecular Weight	1034.98 g/mol
Synonyms	Adenosine 5'-triphosphate lipid conjugate; ATP-lipid conjugate; Nucleotide-phospholipid hybrid; 1,2-Dipalmitoyl-sn-glycero-3-phosphatidyl adenosine triphosphate analog; N6-Amino-ATP-C16 lipid; 5'-ATP-C16 conjugate; Lipid-modified adenosine triphosphate; PAL-ATP (Potential abbreviation)
EINECS	Contact for details

Quality Control

This high-value biochemical is manufactured under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for sensitive research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term stability, store under an inert atmosphere such as argon or nitrogen. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.