Description

[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(2-methylprop-2-enoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid is a high-purity, chemically modified nucleotide derivative designed for advanced research and pharmaceutical development. This compound is critical for applications requiring precise biochemical interactions, such as enzyme studies and the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in drug discovery, molecular biology, and nucleotide-based chemistry.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic assays and metabolic pathway studies.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel antiviral or anticancer nucleotide analogs.
• Proteomics & Genomics: Employed in the development of probes and tools for studying nucleic acid-protein interactions.
• Drug Discovery: Acts as a precursor for creating modified nucleotides with targeted therapeutic activity.
• Diagnostic Reagent Development: Utilized in formulating high-sensitivity assays and diagnostic kits.
• Academic Research: Supports fundamental studies in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(2-methylprop-2-enoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid
CAS No.	6008-91-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Adenosine 5'-(trihydrogen diphosphate), 2'-(4-[[2-[[2-[(2-Methyl-1-oxo-2-propen-1-yl)thio]ethyl]amino]-2-oxoethyl]amino]-4-carboxy-1,1-dimethylbutyl) ester, 3'→5'-ester with 3-hydroxy-2,2-dimethylpropanoic acid; 2'-Deoxyadenosine-5'-triphosphate, α,β-methylene-; ATP analog; Modified nucleotide; Nucleotide derivative; Biochemical reagent; Research chemical.
EINECS	Contact for details

Quality Control

Our [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(2-methylprop-2-enoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.