Description

5,11-Epoxynaphthacene-3-carboxamide, 5a-chloro-1-(dimethylamino)-1,4,4a,5,5a,6,11,11a,12,12a-decahydro-2,4a,5,7,12-pentahydroxy-11-methyl-4,6-dioxo-, monohydrochloride, [1S-(1alpha,4alpha,5beta,5aalpha,11beta,11aalpha,12alpha,12aalpha)]- is a complex, stereochemically defined tetracyclic compound of significant interest in advanced pharmaceutical research and development. This high-purity chemical serves as a critical intermediate or reference standard for the synthesis and study of novel therapeutic agents, particularly in antibiotic and anticancer research. It is essential for R&D laboratories, process chemists, and analytical scientists working on complex molecular scaffolds and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel tetracycline-class antibiotics and other complex bioactive molecules.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new chemical entities (NCEs).
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Structure-Activity Relationship (SAR) Studies: Enables the investigation of how specific stereochemical and functional group modifications affect biological activity.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and chemical biology.

Basic Information

Item	Details
Product Name	5,11-Epoxynaphthacene-3-carboxamide, 5a-chloro-1-(dimethylamino)-1,4,4a,5,5a,6,11,11a,12,12a-decahydro-2,4a,5,7,12-pentahydroxy-11-methyl-4,6-dioxo-, monohydrochloride, [1S-(1alpha,4alpha,5beta,5aalpha,11beta,11aalpha,12alpha,12aalpha)]-
CAS No.	38200-11-2
Molecular Formula	C22H28ClN3O9 • HCl
Molecular Weight	550.84 g/mol
Synonyms	5a-Chloro-1-(dimethylamino)-1,4,4a,5,5a,6,11,11a,12,12a-decahydro-2,4a,5,7,12-pentahydroxy-11-methyl-4,6-dioxo-5,11-epoxynaphthacene-3-carboxamide monohydrochloride; 5a-Chloro-1-(dimethylamino)-1,4,4a,5,5a,6,11,11a,12,12a-decahydro-2,4a,5,7,12-pentahydroxy-11-methyl-4,6-dioxo-5,11:12,11a-diepoxynaphthacene-3-carboxamide hydrochloride; (1S,4S,5R,5aR,11R,11aR,12R,12aR)-5a-Chloro-1-(dimethylamino)-1,4,4a,5,5a,6,11,11a,12,12a-decahydro-2,4a,5,7,12-pentahydroxy-11-methyl-4,6-dioxo-5,11-epoxynaphthacene-3-carboxamide hydrochloride; A derivative of 5,11-Epoxynaphthacene-3-carboxamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5,11-Epoxynaphthacene-3-carboxamide derivative is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.