Description

Carbamic acid, N-[4-amino-5-[[4-[(21-chloro-5,8-dioxo-12,15-dioxa-4,9-diazaheneicos-1-yl)oxy]-3,5-dimethoxyphenyl]methyl]-2-pyrimidinyl]-, [7-(diethylamino)-2-oxo-2H-1-benzopyran-4-yl]methyl ester is a sophisticated synthetic organic compound designed for advanced research and development. This molecule is significant for its complex structure, which integrates a coumarin-derived fluorophore with a functionalized linker, making it a valuable tool in bioconjugation and probe development. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and diagnostic sectors for creating targeted imaging agents, drug delivery systems, and biochemical probes.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and other biomolecules with a fluorescent coumarin tag.
• Fluorescent Probe Synthesis: As a key intermediate in the development of high-sensitivity fluorescent probes and sensors for cellular imaging.
• Drug Discovery & Development: Utilized in the synthesis of targeted therapeutic conjugates, particularly in antibody-drug conjugate (ADC) research.
• Diagnostic Assay Development: For creating fluorescent labels in immunoassays, flow cytometry, and other diagnostic platforms.
• Chemical Biology Research: As a tool compound for studying enzyme activity, protein-protein interactions, and cellular localization.
• Material Science: Potential use in the development of smart polymeric materials and surfaces with responsive fluorescent properties.

Basic Information

Product Name	Carbamic acid, N-[4-amino-5-[[4-[(21-chloro-5,8-dioxo-12,15-dioxa-4,9-diazaheneicos-1-yl)oxy]-3,5-dimethoxyphenyl]methyl]-2-pyrimidinyl]-, [7-(diethylamino)-2-oxo-2H-1-benzopyran-4-yl]methyl ester
CAS No.	2137894-99-4
Molecular Formula	C₅₃H₆₆ClN₇O₁₂
Molecular Weight	1020.58 g/mol
Synonyms	Coumarin-based Bioconjugation Linker; 7-Diethylaminocoumarin-4-carboxylic acid, N-hydroxysuccinimide ester derivative; Fluorescent Labeling Agent 2137894-99-4; Aminopyrimidine-coumarin conjugate; N-[4-Amino-5-[[4-[(21-chloro-5,8-dioxo-12,15-dioxa-4,9-diazaheneicos-1-yl)oxy]-3,5-dimethoxyphenyl]methyl]-2-pyrimidinyl]carbamic acid (7-diethylamino-2-oxo-2H-chromen-4-yl)methyl ester; CAS 2137894-99-4
EINECS	Contact for details

Quality Control

Every batch of this high-purity biochemical reagent is produced and analyzed under strict quality management protocols. Certificates of Analysis (COA) are provided, detailing comprehensive testing via HPLC, NMR, and mass spectrometry to confirm identity, purity, and conformity to customer specifications. Our quality system is designed to support GMP-compliant research and development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.