Description

5-Isoquinolinol,1-[[4,5-dimethoxy-2-[[(6aS)-5,6,6a,7-tetrahydro-1,2,3,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-yl]oxy]phenyl]methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-,(1S)- is a complex, high-purity alkaloid derivative of significant interest in advanced research and development. This compound matters as a sophisticated chemical building block and reference standard for pharmaceutical discovery and biochemical studies. It is primarily needed by R&D chemists and process scientists in the pharmaceutical, biotechnology, and academic research sectors working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), particularly for complex alkaloid-based therapeutics.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate biological pathways and receptor interactions.
• Organic Synthesis: Acts as a versatile, structurally complex building block for synthesizing new chemical entities (NCEs) in medicinal chemistry programs.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Academic Research: Utilized in university and institutional labs for fundamental studies in natural product chemistry, total synthesis, and structure-activity relationship (SAR) analysis.

Basic Information

Item	Details
Product Name	5-Isoquinolinol,1-[[4,5-dimethoxy-2-[[(6aS)-5,6,6a,7-tetrahydro-1,2,3,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-yl]oxy]phenyl]methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-,(1S)-
CAS No.	28328-00-9
Molecular Formula	C41H48N2O9
Molecular Weight	712.84 g/mol
Synonyms	(1S)-1-[[4,5-Dimethoxy-2-[[(6aS)-5,6,6a,7-tetrahydro-1,2,3,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinolin-9-yl]oxy]phenyl]methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-5-isoquinolinol; Berbamine derivative; Tetrandrine analogue; Isoquinoline alkaloid; Oxoisoaporphine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Isoquinolinol derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. Keep the container tightly sealed in its original packaging to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.