Description

6-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-6-oxohexanoic acid is a complex, high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound is critical for its role as a specialized precursor in the synthesis of novel nucleotide-based therapeutics and research probes. It is primarily sought after by biopharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on metabolic pathways, enzyme inhibition, and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine nucleotide analogs and prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, ATPases, and other nucleotide-binding proteins.
• Prodrug Development: Serves as a specialized carrier moiety in the design of targeted prodrugs to enhance cellular uptake and specificity.
• Metabolic Pathway Analysis: A tool for investigating cellular energy metabolism and nucleotide salvage pathways.
• Labeled Compound Synthesis: Precursor for the incorporation of isotopic labels (e.g., 13C, 15N) for tracer studies and metabolic flux analysis.
• High-Throughput Screening (HTS): Component in assay development for drug discovery campaigns targeting nucleotide-dependent processes.

Basic Information

Product Name	6-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-6-oxohexanoic acid
CAS No.	25119-42-0
Molecular Formula	C29H48N7O20P3S
Molecular Weight	939.71 g/mol
Synonyms	6-Mercaptohexanoic acid S-[2-[[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] ester; Pantetheine phosphate adenosine diphosphate derivative; Coenzyme A analog intermediate; (R)-4-[[[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydro-2-furanyl]methoxy(hydroxy)phosphoryl]oxy(hydroxy)phosphoryl]oxy-2-hydroxy-N-[3-[[2-[(6-oxo-6-oxohexyl)thio]ethyl]amino]-3-oxopropyl]-3,3-dimethylbutanamide; ATP-pantetheine adduct
EINECS	Contact for details

Quality Control

This high-value biochemical is manufactured under strict quality control protocols suitable for research and development use. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided and the material can be supplied to meet specific customer requirements for purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize condensation and exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.