Description

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-, mononitrate (salt) is a high-purity, complex tetracycline derivative salt. This compound is valued for its specific stereochemistry and functional groups, which are critical for advanced pharmaceutical research and development. It serves as a key pharmaceutical intermediate or reference standard for organizations engaged in the synthesis of novel antibiotics and the study of bacterial protein synthesis inhibition.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel tetracycline-class antibiotics and related therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of antibiotic products.
• Biochemical Research: Applied in microbiological and pharmacological studies to investigate mechanisms of action against resistant bacterial strains.
• API Development: Utilized in the research and development phase of new Active Pharmaceutical Ingredients (APIs) targeting a broad spectrum of infections.
• Veterinary Medicine Research: Acts as a precursor in the development of advanced antimicrobial treatments for animal health.

Basic Information

Product Name	2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-, [4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-, mononitrate (salt)
CAS No.	20685-78-3
Molecular Formula	C29H40N4O11 • HNO3
Molecular Weight	Contact for details
Synonyms	7-Dimethylamino-6-demethyl-6-deoxytetracycline pyrrolidinomethyl nitrate; Pyrrolidinomethyl Tetracycline Nitrate; NSC 113041; Nitrate salt of Pyrrolidinomethyltetracycline; PMT Nitrate; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-2-naphthacenecarboxamide mononitrate
EINECS	Contact for details

Quality Control

Our 2-Naphthacenecarboxamide derivative mononitrate salt is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.