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[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phosphinic acid CAS NO 2140-58-1


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CAS No.:2140-58-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phosphinic acid is a high-purity nucleotide derivative of significant biochemical importance. This compound serves as a critical building block and research tool in the development of novel therapeutics and diagnostic agents. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on nucleotide chemistry, antiviral drug development, and molecular biology.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and signaling pathways.
  • Pro-drug Development: Serves as a masked or activated form of nucleosides for targeted drug delivery systems.
  • Diagnostic Reagent Synthesis: Building block for labeled nucleotides used in PCR, sequencing, and other molecular diagnostic assays.
  • Enzyme Cofactor Studies: Investigated for its role in modulating enzyme activity in metabolic research.
  • Academic & Industrial R&D: Fundamental material for exploring new chemical entities in medicinal chemistry and life sciences.

Basic Information

Product Name [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phosphinic acid
CAS No. 2140-58-1
Molecular Formula C16H25N5O16P2
Molecular Weight 605.34 g/mol
Synonyms Adenosine 5'-(trihydrogen diphosphate), 2'-(D-glucose 1-phosphate); P1-(2'-Deoxyadenosin-5'-yl) P2-(α-D-glucopyranosyl-1-) diphosphate; Adenosine 5'-diphosphate glucose; ADP-glucose; ADP-D-glucose; ADPG; Adenosine diphosphate glucose; α-D-Glucopyranosyl adenosine 5'-pyrophosphate
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Quality Control

Our [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phosphinic acid is manufactured under strict quality control protocols suitable for research and development applications. Each batch is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, identification, and impurity profiles are available upon request. We support compliance with relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Related Substances (HPLC) Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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