Description

5-[[5-[[2-(Hydroxyimino)-1,1-dimethylpropyl]amino]-3-[2-[[2-(hydroxyimino)-1,1-dimethylpropyl]amino]ethyl]pentyl]amino]-5-oxo-pentanoic Acid 2,3,4,5,6-Pentafluorophenyl Ester is a specialized bifunctional linker molecule designed for advanced bioconjugation and chemical synthesis. Its core value lies in its dual reactive sites, enabling the stable and selective cross-linking of biomolecules or other chemical entities under controlled conditions. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, proteomics, and diagnostic assay production, where precise molecular assembly is critical.

Application

• Bioconjugation Reagent: For the site-specific cross-linking of proteins, antibodies, peptides, and oligonucleotides to create stable conjugates for therapeutic or diagnostic use.
• Proteomics Research: Used in the development of affinity probes, activity-based protein profiling (ABPP), and chemical proteomics to study protein function and interactions.
• Antibody-Drug Conjugate (ADC) Linker Synthesis: Serves as a key intermediate in the construction of sophisticated, cleavable linker-payload systems for targeted cancer therapies.
• Surface Functionalization: Enables the covalent attachment of biomolecules to nanoparticles, biosensors, microarrays, and other solid supports.
• Polymer Modification: Acts as a functional cross-linker to introduce reactive handles or bioactive moieties into polymeric materials for biomedical applications.
• Diagnostic Kit Manufacturing: Integral for producing enzyme-linked immunosorbent assay (ELISA) components, lateral flow assay conjugates, and other immunodiagnostic reagents.

Basic Information

Item	Details
Product Name	5-[[5-[[2-(Hydroxyimino)-1,1-dimethylpropyl]amino]-3-[2-[[2-(hydroxyimino)-1,1-dimethylpropyl]amino]ethyl]pentyl]amino]-5-oxo-pentanoic Acid 2,3,4,5,6-Pentafluorophenyl Ester
CAS No.	1287264-54-3
Molecular Formula	C27H40F5N5O5
Molecular Weight	609.64 g/mol
Synonyms	Pentafluorophenyl Ester Bifunctional Linker; PFPE Crosslinker; N-Hydroxysuccinimide (NHS) Ester Alternative; Hydroxyimino-based Heterobifunctional Linker; 5-Oxo-pentanoic Acid Pentafluorophenyl Ester Derivative; CAS 1287264-54-3; Bioconjugation Agent 1287264-54-3
EINECS	Contact for details

Quality Control

Our 5-[[5-[[2-(Hydroxyimino)-1,1-dimethylpropyl]amino]-3-[2-[[2-(hydroxyimino)-1,1-dimethylpropyl]amino]ethyl]pentyl]amino]-5-oxo-pentanoic Acid 2,3,4,5,6-Pentafluorophenyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This compound is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.