Description

Farnesylpyrophosphate CAS NO 13058-04-3 is a critical 15-carbon isoprenoid diphosphate intermediate in the mevalonate pathway. This compound serves as the universal precursor for the biosynthesis of sesquiterpenes, sterols, dolichols, and prenylated proteins, making it indispensable for cellular function and signaling. It is a high-value biochemical reagent primarily required by researchers and manufacturers in pharmaceutical development, metabolic studies, and enzymology.

Application

• Enzymatic Substrate for Research: Essential substrate for studies involving farnesyltransferase, geranylgeranyltransferase, and terpene synthases.
• Pharmaceutical R&D: Used in the development and screening of inhibitors targeting cholesterol biosynthesis, cancer (Ras protein prenylation), and bone disorders (bisphosphonate research).
• Metabolic Pathway Analysis: A key intermediate for investigating the mevalonate pathway in cell biology, microbiology, and plant biochemistry.
• Synthesis of Complex Biomolecules: Serves as a building block for the in vitro enzymatic synthesis of sesquiterpenoids and other isoprenoid compounds.
• Biochemical Assay Standard: Used as a purity standard and calibrant in analytical methods such as LC-MS for metabolic profiling.

Basic Information

Product Name	Farnesylpyrophosphate
CAS No.	13058-04-3
Molecular Formula	C15H28O7P2
Molecular Weight	382.33 g/mol
Synonyms	Farnesyl Diphosphate; FPP; trans,trans-Farnesyl Pyrophosphate; (2E,6E)-Farnesyl Diphosphate; (all-E)-Farnesyl Diphosphate; Farnesyl Diphosphoric Acid; NSC 89176; Isopentenyl Pyrophosphate Homolog
EINECS	235-942-8

Quality Control

Our Farnesylpyrophosphate is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization including HPLC purity assay, NMR identification, and mass spectrometry confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee product integrity and support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or ammonium salt
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.