Description

1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide is a versatile and highly effective zero-length coupling agent widely used in peptide synthesis and bioconjugation. Its primary value lies in facilitating the formation of amide bonds between carboxylic acids and amines under mild conditions, making it indispensable for creating complex biomolecules. This reagent is critical for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries, enabling the development of novel therapeutics, diagnostic agents, and advanced research materials.

Application

• Peptide Synthesis: As a key coupling reagent (often used with HOBt or HOAt) for solid-phase and solution-phase peptide synthesis.
• Protein Cross-linking & Bioconjugation: For creating stable conjugates of proteins, antibodies, or enzymes with other molecules like drugs, dyes, or polymers.
• Nucleic Acid Modification: In the preparation of labeled probes or oligonucleotide conjugates for diagnostic and research applications.
• Polymer & Material Science: For modifying polymer surfaces or synthesizing specialized polymeric materials with specific functional groups.
• Carbohydrate Chemistry: Used in the synthesis of glycoconjugates and other complex carbohydrate derivatives.
• General Organic Synthesis: As a dehydrating agent for the preparation of esters, anhydrides, and other acid derivatives from carboxylic acids.

Basic Information

Product Name	1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide
CAS No.	1892-57-5
Molecular Formula	C8H17N3
Molecular Weight	155.24 g/mol
Synonyms	EDC; EDAC; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide; 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide; 3-(Ethyliminomethyleneamino)-N,N-dimethylpropan-1-amine; N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide; WSC; Water-soluble carbodiimide; N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide
EINECS	217-575-7

Quality Control

Our 1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and efficacy. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.