Description

Thiourea, N-6-O-(N-acetyl-.alpha.-neuraminosyl)-(26)-O-.beta.-D-galactopyranosyl-(14)-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyloxyhexyl-N-(3,6-dihydroxy-3-oxospiroisobenzofuran-1(3H),9-9Hxanthen-5-yl)-, disodium salt is a sophisticated, high-purity synthetic glycosylated thiourea derivative designed for advanced research and diagnostic applications. This compound is engineered to provide a highly specific and sensitive molecular tool, particularly valued for its role as a fluorescently labeled probe or substrate. It is primarily utilized by researchers and developers in the fields of glycobiology, enzymology, and diagnostic assay development. The product is supplied with a commitment to batch-to-batch consistency and analytical verification to support critical experimental outcomes.

Application

• Enzyme Substrate for Glycosidases: Used as a specific, fluorescently tagged substrate for studying the activity and kinetics of neuraminidases (sialidases) and other glycosyl hydrolases.
• Glycobiology Research: Serves as a critical tool for investigating carbohydrate-protein interactions, cell surface labeling, and glycan biosynthetic pathways.
• Diagnostic Assay Development: Employed in the development of high-throughput screening (HTS) assays and diagnostic kits for detecting enzymatic activity related to infectious diseases or genetic disorders.
• Biochemical Probe: Acts as a fluorescent probe for imaging and detection applications in cellular and microbiological studies.
• Pharmaceutical Research: Utilized in drug discovery programs targeting viral neuraminidases (e.g., influenza) or other carbohydrate-processing enzymes.
• Quality Control Reference Standard: Functions as a certified reference material (CRM) for calibrating analytical methods in biotechnology and pharmaceutical quality control labs.

Basic Information

Product Name	Thiourea, N-6-O-(N-acetyl-.alpha.-neuraminosyl)-(26)-O-.beta.-D-galactopyranosyl-(14)-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyloxyhexyl-N-(3,6-dihydroxy-3-oxospiroisobenzofuran-1(3H),9-9Hxanthen-5-yl)-, disodium salt
CAS No.	184294-04-0
Molecular Formula	C58H71N5O26S·2Na
Molecular Weight	~1365.24 g/mol (Disodium salt form)
Synonyms	5-Carboxyfluorescein labeled Sialyl LacNAc thiourea, disodium salt; Fluorescein-labeled Sialyl Lewis X precursor; 5(6)-FAM-Sia-α-2,6-Gal-β-1,4-GlcNAc-thiourea; Glycosylated thiourea-fluorescein conjugate; Sialyl-N-acetyllactosamine-fluorescein derivative; 6'--Sialyllactosamine-5-FAM thiourea; FSA (Fluorescent Sialylglycoconjugate); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this high-value biochemical is produced and analyzed under strict quality control protocols to ensure identity, purity, and performance. Our quality system is designed to meet the exacting requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from advanced analytical techniques including HPLC, MS, and NMR for full structural confirmation and purity assessment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Orange to red solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area % at 254 nm / 495 nm)
Assay (UV-Vis)	≥ 90% (by extinction coefficient)
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Functional as enzyme substrate (Data provided)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.