Description

(2S,3S,4S,5R,6R)-6-(4-amino-2-oxo-pyrimidin-1-yl)-3-[[(2R)-3-(diaminomethylideneamino)-2-[(2-methylaminoacetyl)amino]propanoyl]amino]-4,5-dihydroxy-oxane-2-carboxamide is a high-purity, complex nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and biotechnology companies engaged in the development of next-generation nucleotide-based therapies and molecular probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and specific cancers.
• Antiviral Drug Research: Used as a key scaffold for developing potential inhibitors of viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a building block for creating targeted chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate or inhibitor in assays to study nucleotide metabolism and related pathways.
• Molecular Probe Development: Utilized in the design and synthesis of labeled compounds for diagnostic imaging or target engagement studies.
• Pre-clinical Candidate Synthesis: Integral to medicinal chemistry programs for the preparation of lead optimization candidates and pre-clinical trial materials.

Basic Information

Product Name	(2S,3S,4S,5R,6R)-6-(4-amino-2-oxo-pyrimidin-1-yl)-3-[[(2R)-3-(diaminomethylideneamino)-2-[(2-methylaminoacetyl)amino]propanoyl]amino]-4,5-dihydroxy-oxane-2-carboxamide
CAS No.	104840-35-9
Molecular Formula	C17H26N8O8
Molecular Weight	470.44 g/mol
Synonyms	1-(2S,3S,4S,5R,6R)-3-[[(2R)-3-(Diaminomethylideneamino)-2-[(2-methylaminoacetyl)amino]propanoyl]amino]-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-4-aminopyrimidin-2-one; Complex Nucleoside Amide Derivative; N6-Methyl-2'-deoxycytidine Guanidino Analog (structural description); Advanced Nucleoside Intermediate; CAS 104840-35-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development purposes. While typically supplied as a high-purity research grade, specifications can be aligned with cGMP guidelines for pharmaceutical applications upon request. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.