Description

2-Methoxy-5-Fluorouracil is a fluorinated pyrimidine derivative, a key intermediate in the synthesis of more complex nucleoside analogs and active pharmaceutical ingredients (APIs). This compound matters for its role in medicinal chemistry research, particularly in the development of novel anticancer and antiviral agents. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity building block to explore new therapeutic pathways and scale up production processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and other potential anticancer drugs.
• Medicinal Chemistry Research: Used as a building block in drug discovery programs targeting thymidylate synthase and other enzymes involved in DNA synthesis.
• Biochemical Research: Serves as a tool compound for studying cell proliferation, nucleotide metabolism, and the mechanisms of fluoropyrimidine-based therapies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized fluorouracil derivatives.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	2-Methoxy-5-Fluorouracil
CAS No.	1480-96-2
Molecular Formula	C5H5FN2O3
Molecular Weight	160.10 g/mol
Synonyms	5-Fluoro-2-methoxyuracil; 5-Fluoro-2-methoxy-1H-pyrimidine-2,4-dione; 2-Methoxy-5-fluoropyrimidine-4,6(1H,5H)-dione; NSC 154020; 5-Fluoro-2-methoxy-4-pyrimidinol; 2-Methoxy-5-fluorouracil
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-Fluorouracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.