Description

3'-Deoxy-5-Fluorouridine is a fluorinated nucleoside analog with significant biochemical and pharmacological interest. This compound is valued for its role as a key intermediate in the synthesis of more complex antiviral and anticancer agents, where its modified sugar moiety is critical for biological activity. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic nucleosides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Antiviral Agent Development: Serves as a precursor in the research and development of novel compounds targeting viral polymerases.
• Oncology Research: Investigated for its potential cytotoxic properties and as a model compound for studying the mechanism of fluoropyrimidines.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialty nucleosides.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3'-Deoxy-5-Fluorouridine
CAS No.	18829-83-9
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine 3'-deoxy derivative; 3'-Deoxy-5-fluorouridine; 5-Fluoro-3'-deoxyuridine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-(3-deoxy-β-D-ribofuranosyl)uracil; NSC 112907; 3'-d-5-FUrd
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-5-Fluorouridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.