Description

(2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,11β,13α-hexahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester is a complex tetracycline-class derivative, recognized for its intricate stereochemistry and functional group array. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a synthetic intermediate or a structural template for novel bioactive molecules. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized antibiotics or the exploration of new therapeutic agents.

Application

• Pharmaceutical Research Intermediate: Serves as a key synthetic building block in the development of novel tetracycline-derived antibiotics and other therapeutic agents.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control, method development, and regulatory compliance in pharmaceutical analysis.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the impact of specific stereocenters and functional groups on biological activity.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic synthesis, chemical biology, and antibiotic mechanisms.
• Process Chemistry Development: Acts as a model compound for developing and optimizing scalable synthetic routes for complex polycyclic molecules.

Basic Information

Product Name	(2R)-4α-(Dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3β,5β,8,10,11β,13α-hexahydroxy-6,13-dimethyl-9,16-dioxo-2α,6α-epoxy-2H-naphthaceno[1,2-b]oxocin-14α-carboxylic acid methyl ester
CAS No.	11052-70-3
Molecular Formula	C₂₈H₃₅NO₁₂
Molecular Weight	565.58 g/mol
Synonyms	Methyl (2R,3S,4S,5R,6R,8S,10S,11R,12R,13S,14R)-4-(Dimethylamino)-3,5,6,8,10,11,12,13,14,16-decahydro-3,5,8,10,11,13-hexahydroxy-6,13-dimethyl-9,16-dioxo-2,6-epoxy-2H-naphthaceno[1,2-b]oxocine-14-carboxylate; 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline methyl ester derivative; Anhydrotetracycline methyl ester analog; ATC methyl ester; Tetracycline research compound 11052-70-3.
EINECS	Contact for details

Quality Control

Every batch of this advanced chemical intermediate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical research and development work. Our quality systems are designed to support cGMP and ISO standards where applicable, providing the documentation rigor required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.