Description

S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (E)-dodec-2-enethioate is a sophisticated nucleotide-based biochemical building block designed for advanced research and development. This compound is critical for scientists exploring novel pathways in cellular signaling, enzyme regulation, and targeted drug delivery systems. It is primarily utilized by researchers in pharmaceutical development, biochemical synthesis, and academic research focused on nucleotide chemistry and prodrug design.

Application

• Biochemical Research & Development: Serves as a key intermediate or precursor in the synthesis of novel nucleotide analogs and prodrugs for investigative studies.
• Pharmaceutical Development: Used in the research and development of targeted therapeutic agents, particularly in oncology and antiviral drug discovery programs.
• Enzyme Substrate Studies: Acts as a specialized substrate or inhibitor for studying the activity and mechanism of specific kinases, transferases, or other nucleotide-processing enzymes.
• Prodrug Synthesis: Employed in the design and synthesis of prodrug candidates, where its structure can be leveraged for improved bioavailability or targeted activation.
• Cell Signaling Pathway Analysis: Utilized as a tool compound to modulate or trace intracellular signaling cascades involving nucleotide second messengers.
• Academic & Institutional Research: A vital reagent for universities and research institutes conducting fundamental research in bioorganic and medicinal chemistry.

Basic Information

Product Name	S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (E)-dodec-2-enethioate
CAS No.	1066-12-2
Molecular Formula	C₃₀H₅₀N₇O₁₆P₃S
Molecular Weight	913.75 g/mol
Synonyms	Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-, 5'→5'-ester with 3-[[4-[[2-[[(1E)-1-dodecen-1-yl]thio]ethyl]amino]-3-hydroxy-3-methyl-1-oxobutyl]amino]propanoic acid; 2'-Deoxyadenosine-5'-triphosphate derivative; Nucleotide-lipid conjugate; ATP prodrug intermediate; Custom nucleotide analog; CAS 1066-12-2
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.