Description

n-{2-[2-(2-(2-Aminoethoxy)Ethoxy)Ethoxy]Ethyl}Biotinamide Trifluoroacetate Salt is a high-purity, functionalized biotin derivative designed for advanced bioconjugation and molecular labeling applications. This compound is critical for researchers and manufacturers requiring precise, stable attachment of biotin to biomolecules, enabling downstream detection, purification, and analysis. It is primarily utilized in the development of diagnostic assays, targeted drug delivery systems, and advanced life science research tools.

Application

• Bioconjugation Reagent: For the site-specific labeling of antibodies, proteins, peptides, and oligonucleotides with biotin.
• Diagnostic Assay Development: A key intermediate in the production of biotinylated probes and capture molecules for ELISA, lateral flow tests, and other immunoassays.
• Drug Delivery & Targeting: Used in the synthesis of biotin-drug conjugates for targeted therapies leveraging biotin receptor-mediated uptake.
• Affinity Purification Systems: Synthesis of ligands for immobilization on streptavidin/avidin resins for the purification of biomolecules.
• Cell Surface Labeling: Modification of cell surface proteins or lipids for tracking and isolation in flow cytometry and microscopy.
• Material Science Functionalization: Surface modification of nanoparticles, polymers, and other materials to introduce biotin handles for biomolecule attachment.

Basic Information

Product Name	n-{2-[2-(2-(2-Aminoethoxy)Ethoxy)Ethoxy]Ethyl}Biotinamide Trifluoroacetate Salt
CAS No.	945462-84-0
Molecular Formula	C21H37F3N4O7S
Molecular Weight	546.60 g/mol
Synonyms	Biotin-PEG4-amine TFA salt; Biotinamido-PEG4-amine TFA; Biotin-PEG4-NH2 TFA; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]pentanamide trifluoroacetate; Biotinylated Tetraethylene Glycol Amine TFA Salt; N-(2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl)-5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanamide trifluoroacetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request. We adhere to GMP principles for the manufacture of materials intended for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.