Description

Nbd-Fructose CAS NO 940961-04-6 is a fluorescently labeled derivative of the monosaccharide fructose, designed for advanced biochemical research and diagnostic applications. This compound is critical for scientists requiring high-sensitivity detection and tracking of carbohydrate metabolism and transport processes. It is primarily utilized by researchers in pharmaceutical development, life sciences, and diagnostic kit manufacturing who need precise, reliable probes for glycosylation studies, enzyme assays, and cellular imaging.

Application

• Biochemical Research Probe: Used as a fluorescent tracer in studies of fructose uptake, transport, and metabolism in cell cultures and tissue samples.
• Enzyme Activity Assays: Serves as a substrate or inhibitor in high-throughput screening (HTS) for enzymes like ketohexokinase (KHK) or fructokinase.
• Glycobiology Studies: Essential for investigating protein glycosylation pathways, lectin binding, and carbohydrate-protein interactions via fluorescence detection.
• Diagnostic Development: Employed in the development of fluorescent-based diagnostic assays and kits for metabolic disorders such as hereditary fructose intolerance.
• Cellular Imaging: Acts as a vital tool for visualizing and quantifying fructose localization and dynamics within live or fixed cells using fluorescence microscopy.
• Pharmaceutical R&D: Used in drug discovery programs targeting carbohydrate metabolism, particularly for metabolic diseases, diabetes, and cancer research.

Basic Information

Product Name	Nbd-Fructose
CAS No.	940961-04-6
Molecular Formula	C₁₆H₁₈N₄O₈
Molecular Weight	394.34 g/mol
Synonyms	7-Nitrobenz-2-oxa-1,3-diazol-4-yl Fructose; NBD-Fructose; 4-(2,3,4,5-Tetrahydroxypentyl)-7-nitro-2,1,3-benzoxadiazole; Fluorescent Fructose Derivative; NBD-Labeled Fructose; Fructose-NBD; NBD-F
EINECS	Contact for details

Quality Control

Every batch of Nbd-Fructose is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to support research and regulatory needs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.