Description

Argpyrimidine CAS NO 936233-19-1 is a high-purity advanced glycation end-product (AGE) derived from arginine and methylglyoxal, serving as a critical reference standard and research chemical. Its value lies in enabling precise study of protein glycation, oxidative stress, and metabolic pathways associated with aging and chronic diseases. This compound is essential for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors focused on diabetes, neurodegeneration, and cardiovascular research.

Application

• Biomedical Research Standard: Primary application as a certified reference material (CRM) for the quantification and validation of AGEs in biological samples.
• Diagnostic Kit Development: Used as a key antigen or calibrator in the development of immunoassays and ELISA kits for detecting glycation biomarkers.
• Metabolic Disease Studies: Critical for in-vitro and in-vivo research into the mechanisms of diabetes, uremia, and age-related pathologies.
• Pharmaceutical QC: Serves as an impurity standard and system suitability marker in the analysis of drug products and formulations.
• Nutritional Science: Employed in studies investigating the impact of diet and food processing on the formation of dietary AGEs.
• Anti-AGE Drug Discovery: Used as a target compound for screening and evaluating potential therapeutic agents designed to inhibit or break AGE cross-links.

Basic Information

Product Name	Argpyrimidine
CAS No.	936233-19-1
Molecular Formula	C9H14N4O2
Molecular Weight	210.24 g/mol
Synonyms	Nδ-(5-Hydroxy-4,6-dimethylpyrimidine-2-yl)-L-ornithine; L-Ornithine, N5-(5-hydroxy-4,6-dimethyl-2-pyrimidinyl)-; Arg-pyr; AGE-Argpyrimidine; Methylglyoxal-Arg pyrimidine; MG-Argpyrimidine; Advanced Glycation Endproduct Argpyrimidine
EINECS	Contact for details

Quality Control

Our Argpyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized and confirmed using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under desiccated conditions. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.