Description

9-Amino-(9-Deoxy)Epi-Dihydroquinidine Trihydrochloride is a high-purity, advanced pharmaceutical intermediate derived from the cinchona alkaloid family. This compound is valued for its role as a key chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel catalysts.

Application

• Asymmetric Synthesis Catalyst: Serves as a chiral ligand or organocatalyst in stereoselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex, biologically active molecules and potential APIs.
• Chiral Resolution Agent: Used in the separation and purification of enantiomers through diastereomeric salt formation or chiral chromatography.
• Academic & Industrial Research: A valuable tool for method development and exploring new catalytic systems in synthetic organic chemistry laboratories.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9-Amino-(9-Deoxy)Epi-Dihydroquinidine Trihydrochloride
CAS No.	931098-92-9
Molecular Formula	C20H29Cl3N4O
Molecular Weight	453.82 g/mol
Synonyms	9-Amino-9-deoxyepi-dihydroquinidine trihydrochloride; (8α,9R)-10,11-Dihydro-6'-methoxy-9-amino-9-deoxycinchonan trihydrochloride; 9-ADEDQ trihydrochloride; 9-Amino-9-deoxy-epi-dihydroquinidine hydrochloride (1:3); 9-Aminoepi-dihydroquinidine trihydrochloride; (8α,9R)-9-Amino-10,11-dihydro-6'-methoxycinchonan trihydrochloride
EINECS	Contact for details

Quality Control

Our 9-Amino-(9-Deoxy)Epi-Dihydroquinidine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.