Description

(2R)-(-)-1-Benzoyl-2-tert-Butyl-3-Methyl-4-Imidazolidinone is a high-purity chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its value lies in its ability to induce high enantioselectivity in a variety of catalytic and stoichiometric transformations, enabling the production of single-enantiomer compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for complex molecule synthesis.

Application

• As a chiral auxiliary in the stereoselective synthesis of pharmaceutical active ingredients (APIs).
• As a key ligand or precursor for asymmetric catalysts used in hydrogenation, alkylation, and aldol reactions.
• In the research and development of novel therapeutic compounds, including those targeting central nervous system (CNS) disorders.
• For the preparation of enantiomerically pure intermediates in agrochemical and fragrance manufacturing.
• As a standard or reference material in analytical method development for chiral separation techniques (e.g., HPLC, SFC).
• In academic and industrial research focused on methodology development for new asymmetric transformations.

Basic Information

Product Name	(2R)-(-)-1-Benzoyl-2-tert-Butyl-3-Methyl-4-Imidazolidinone
CAS No.	101055-57-6
Molecular Formula	C16H22N2O2
Molecular Weight	274.36 g/mol
Synonyms	(2R)-1-Benzoyl-2-(tert-butyl)-3-methylimidazolidin-4-one; (R)-1-Benzoyl-2-tert-butyl-3-methylimidazolidin-4-one; (R)-(-)-1-Benzoyl-2-tert-butyl-3-methyl-4-imidazolidinone; (R)-BTM; (R)-N-Benzoyl-tert-butyl-3-methylimidazolidinone; Evans Auxiliary Derivative; Chiral Imidazolidinone Auxiliary
EINECS	Contact for details

Quality Control

Our (2R)-(-)-1-Benzoyl-2-tert-Butyl-3-Methyl-4-Imidazolidinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.