Description

D(-)-Glutamic Acid is the enantiomer of the essential amino acid L-glutamic acid, characterized by its specific optical rotation. This high-purity chiral building block is critical for applications requiring precise stereochemistry, such as pharmaceutical synthesis and biochemical research. It serves as a key intermediate for producing peptides, active pharmaceutical ingredients (APIs), and specialized nutritional supplements, meeting the stringent demands of the life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of specific peptide-based drugs, active pharmaceutical ingredients (APIs), and diagnostic agents.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and neuroscience research related to glutamate receptors.
• Nutritional Science: Employed in specialized nutritional studies and the development of enantiomerically defined dietary supplements or amino acid formulations.
• Fine Chemical Synthesis: Serves as a building block for synthesizing complex organic molecules, catalysts, and ligands where the D-configuration is required.
• Cosmetic & Personal Care: Potential use in high-end skincare formulations as a component of moisturizing or skin-conditioning agents.

Basic Information

Product Name	D(-)-Glutamic Acid
CAS No.	6893-26-1
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	D-Glutamic Acid; (R)-2-Aminopentanedioic Acid; (R)-Glutamic Acid; D-(-)-Glutamic Acid; (2R)-2-Aminoglutaric Acid; H-D-Glu-OH; D-Glu; D-Glutaminsäure
EINECS	229-994-8

Quality Control

Our D(-)-Glutamic Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specific results for identity, purity, optical rotation, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-30.0° to -34.0° (c=1 in 5N HCl)
Chiral Purity (D-Isomer)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.