Description

(S)-γ-Methyl-γ-Butyrolactone CAS NO 19041-15-7 is a high-value, chiral lactone building block essential for asymmetric synthesis. This optically pure compound serves as a critical intermediate in the production of advanced pharmaceuticals and fine chemicals, enabling the creation of molecules with specific, desired biological activities. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a versatile building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemicals: Employed in the research and development of chiral pesticides and herbicides where specific stereochemistry impacts efficacy and environmental profile.
• Flavor & Fragrance Industry: Acts as a precursor for the synthesis of specific lactone-based aroma compounds.
• Ligand & Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in catalytic asymmetric transformations.
• Material Science Research: Investigated as a monomer or precursor for synthesizing specialized polymers with unique optical or mechanical properties.

Basic Information

Product Name	(S)-γ-Methyl-γ-Butyrolactone
CAS No.	19041-15-7
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(S)-γ-Methyl-γ-butyrolactone; (S)-4-Methyldihydrofuran-2(3H)-one; (S)-4-Methylbutyrolactone; (S)-Pantolactone; (S)-3-Methylbutyrolactone; (S)-4-Methyl-γ-butyrolactone; (S)-4-Methyloxolan-2-one; (S)-(-)-γ-Methyl-γ-butyrolactone
EINECS	Contact for details

Quality Control

Our (S)-γ-Methyl-γ-Butyrolactone is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and GC, to verify identity, purity, and optical rotation. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.