Description

(R)-(+)-1,2-Diaminopropane Dihydrochloride is a high-purity chiral diamine salt, serving as a critical building block in asymmetric synthesis and pharmaceutical development. Its enantiomeric purity makes it an indispensable ligand and resolving agent for creating optically active compounds. This material is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and antibiotics.
• Asymmetric Catalyst Ligand: Used to prepare chiral metal complexes for enantioselective catalysis, including hydrogenation and alkylation reactions.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of carboxylic acids and other acidic compounds via diastereomeric salt formation.
• Fine Chemical Synthesis: A versatile building block for constructing complex molecules with defined stereochemistry in agrochemicals and specialty chemicals.
• Bioconjugation & Linker Chemistry: Utilized in bioconjugation strategies and as a linker moiety in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals.
• Research & Development: A valuable reagent in academic and industrial R&D for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-(+)-1,2-Diaminopropane Dihydrochloride
CAS No.	19777-67-4
Molecular Formula	C₃H₁₀N₂·2HCl
Molecular Weight	155.04 g/mol
Synonyms	(R)-(+)-1,2-Propanediamine Dihydrochloride; (R)-1,2-Diaminopropane Dihydrochloride; D-(+)-1,2-Diaminopropane Dihydrochloride; (2R)-1,2-Diaminopropane Dihydrochloride; (R)-Propane-1,2-diamine Dihydrochloride; (R)-1,2-Propylenediamine Dihydrochloride; (R)-(+)-Propylenediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(+)-1,2-Diaminopropane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.