Description

(R)-(+)-1-Benzyl-3-Pyrrolidinol is a chiral pyrrolidine derivative of significant importance in asymmetric synthesis. This compound serves as a versatile chiral building block and ligand precursor for the production of high-value pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular disorders.
• Asymmetric Catalyst Ligand: Used as a precursor for developing chiral ligands in transition metal catalysis, enabling enantioselective transformations like hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Integral for constructing complex molecular architectures in fragrance, dye, and advanced material research.
• Academic & Process Research: A valuable tool in medicinal chemistry and process development for exploring new synthetic routes and optimizing enantiomeric purity.

Basic Information

Product Name	(R)-(+)-1-Benzyl-3-Pyrrolidinol
CAS No.	101930-07-8
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(R)-1-Benzyl-3-pyrrolidinol; (R)-(+)-1-Benzyl-3-hydroxypyrrolidine; (3R)-1-Benzylpyrrolidin-3-ol; (+)-(R)-1-Benzyl-3-pyrrolidinol; 1-Benzyl-3-pyrrolidinol, (R)-(+)-; (R)-1-Benzyl-3-pyrrolidinol; (R)-3-Hydroxy-1-benzylpyrrolidine; 1-Benzyl-(3R)-pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Benzyl-3-Pyrrolidinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability, as the compound is easily oxidized. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.