Description

(4S)-(-)-4-Isopropyl-2-Oxazolidinone is a high-value chiral auxiliary and building block widely used in asymmetric synthesis. Its importance lies in its ability to induce high stereoselectivity in critical organic transformations, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity chiral reagents.

Application

• As a chiral auxiliary in the Evans aldol reaction and related asymmetric alkylations for the synthesis of complex natural products and drug intermediates.
• As a key building block in the preparation of β-amino alcohols and other pharmacologically active chiral molecules.
• For the resolution of racemic mixtures and the development of novel asymmetric catalysts and ligands.
• In process chemistry for the scale-up and manufacturing of enantiopure active pharmaceutical ingredients (APIs).
• As a reagent in academic and industrial research focused on stereochemistry and synthetic methodology development.

Basic Information

Product Name	(4S)-(-)-4-Isopropyl-2-Oxazolidinone
CAS No.	17016-83-0
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(4S)-4-(1-Methylethyl)-2-oxazolidinone; (S)-4-Isopropyl-2-oxazolidinone; L-4-Isopropyl-2-oxazolidinone; (S)-(-)-4-Isopropyl-2-oxazolidinone; Evans Chiral Auxiliary (S-form); (S)-4-Isopropyloxazolidin-2-one; (4S)-4-Isopropyloxazolidin-2-one; (S)-4-(Propan-2-yl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (4S)-(-)-4-Isopropyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical assay, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Melting Point	86 - 90 °C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.