Description

(R)-2,2-Dimethyl-1-Phenylpropan-1-Amine Hydrochloride CAS NO 19068-35-0 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereocenter essential for creating enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for biological activity and environmental safety.
• Catalyst and Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(R)-2,2-Dimethyl-1-Phenylpropan-1-Amine Hydrochloride
CAS No.	19068-35-0
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(R)-α,α-Dimethylbenzenemethanamine Hydrochloride; (R)-1-Amino-2,2-dimethyl-1-phenylpropane Hydrochloride; (R)-2,2-Dimethyl-1-phenylethylamine Hydrochloride; (R)-Neopentylbenzylamine Hydrochloride; (R)-1-Phenyl-2,2-dimethylpropylamine Hydrochloride; (R)-Pivalylbenzylamine Hydrochloride; (R)-2-Phenyl-3,3-dimethylbutan-2-amine Hydrochloride; (R)-NSC 403914 Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2,2-Dimethyl-1-Phenylpropan-1-Amine Hydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.