Description

(S)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid is a high-value chiral building block and protected form of (S)-glyceric acid. This compound is essential for the stereoselective synthesis of complex molecules, offering a crucial handle for introducing specific three-dimensional architecture. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), nucleoside analogs, and other biologically active compounds.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of antiviral drugs, protease inhibitors, and other enantiomerically pure therapeutics.
• Nucleoside and Nucleotide Chemistry: Used in the synthesis of modified nucleosides for antiviral and anticancer research applications.
• Asymmetric Synthesis: Serves as a versatile chiral synthon for constructing complex natural products and fine chemicals with defined stereochemistry.
• Bioconjugate and Ligand Development: Employed in creating chiral ligands for catalysis and in the development of targeted bioconjugates.
• Academic and R&D Laboratories: Utilized in medicinal chemistry research for exploring new synthetic pathways and drug candidates.

Basic Information

Product Name	(S)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid
CAS No.	102045-96-5
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	(S)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid; (4S)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid; (S)-Glyceric acid 1,2-acetonide; L-Glyceric acid 1,2-acetonide; (S)-Acetonide glyceric acid; (S)-1,2-O-Isopropylidene glyceric acid; (S)-Dioxolane carboxylic acid; (S)-DMDC acid
EINECS	Contact for details

Quality Control

We supply (S)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid in high-purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with research and cGMP starting material standards where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profile is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.