Description

1-(4-Aminobutanoyl)-4-[1,3-Bis(Dihydroxyphosphoryloxy)Propan-2-Yloxy]-7-Nitroindoline is a specialized, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring both nitroindoline and phosphorylated glycerol moieties, makes it a valuable precursor for the synthesis of novel bioactive compounds. This product is primarily targeted at R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors, where it is used to create potential new chemical entities. We supply this material with a focus on consistent quality, batch-to-batch reproducibility, and reliable global logistics to support critical research timelines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Pro-drug Synthesis: The phosphorylated side chain is instrumental in designing pro-drugs with enhanced bioavailability or targeted delivery mechanisms.
• Chemical Biology Research: Used as a tool compound or a precursor for probes to study enzyme inhibition, signal transduction, and cellular processes.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation: The reactive functional groups allow for potential conjugation to peptides, proteins, or other biomolecules for diagnostic or therapeutic applications.

Basic Information

Product Name	1-(4-Aminobutanoyl)-4-[1,3-Bis(Dihydroxyphosphoryloxy)Propan-2-Yloxy]-7-Nitroindoline
CAS No.	927866-58-8
Molecular Formula	C16H25N3O12P2
Molecular Weight	521.33 g/mol
Synonyms	7-Nitro-1-(4-aminobutanoyl)-4-[2,3-bis(phosphonooxy)propoxy]indoline; 4-[1,3-Bis(phosphonooxy)propan-2-yloxy]-1-(4-aminobutanoyl)-7-nitroindoline; 1-(4-Aminobutyryl)-4-[2,3-bis(dihydroxyphosphoryloxy)propoxy]-7-nitroindoline; (7-Nitro-2,3-dihydro-1H-indol-1-yl)-4-oxobutyl-2,3-bis(phosphonooxy)propyl ether; Research Grade 927866-58-8
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Aminobutanoyl)-4-[1,3-Bis(Dihydroxyphosphoryloxy)Propan-2-Yloxy]-7-Nitroindoline is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity with client specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and cGMP-grade production needs, with documentation tailored to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.