Description

1,3-Di-Haba Kanamycin A is a chemically modified derivative of the aminoglycoside antibiotic kanamycin A, specifically functionalized at the 1 and 3 positions. This derivative is primarily utilized as a critical intermediate or reference standard in advanced pharmaceutical research and development. It is essential for scientists and manufacturers engaged in the synthesis of novel antibiotic compounds, mechanism of action studies, and analytical method development. The compound's defined structure makes it a valuable tool for targeting specific bacterial pathways and overcoming resistance mechanisms.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for developing next-generation aminoglycoside antibiotics.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of kanamycin derivatives and their interaction with bacterial ribosomes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis using techniques like HPLC and LC-MS.
• Antibiotic Development: Employed in R&D programs aimed at creating new antimicrobial agents with improved efficacy against resistant bacterial strains.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and microbiology.

Basic Information

Product Name	1,3-Di-Haba Kanamycin A
CAS No.	927821-99-6
Molecular Formula	C18H36N6O11
Molecular Weight	512.51 g/mol
Synonyms	1,3-Di-(4-hydroxybenzamido)kanamycin A; Kanamycin A, 1,3-bis(4-hydroxybenzoyl) derivative; 1,3-Di-HABA-Kanamycin A; 1,3-Bis-O-(4-hydroxybenzoyl)kanamycin A; 4-Hydroxybenzoic acid (1,3)-kanamycin A diester; 927821-99-6; 1,3-Di(4-hydroxybenzamido)kanamycin A
EINECS	Contact for details

Quality Control

Our 1,3-Di-Haba Kanamycin A is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data and batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material at 2-8°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.