Description

(S)-n-((S)-1-(tert-Butyldimethylsilyloxy)But-3-En-2-Yl)-2-Methylpropane-2-Sulfinamide CAS NO 926660-07-3 is a high-value, chiral sulfinamide building block used in sophisticated asymmetric synthesis. This compound is critical for the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Serves as a key reagent for the stereocontrolled introduction of nitrogen and carbon centers in target molecules.
• Pharmaceutical Intermediate: Used in the research and production of enantiomerically pure drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal activity and environmental safety.
• Fine Chemical and Specialty Chemical Production: Acts as a precursor for complex natural products, flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and catalysis studies within university and corporate laboratories.
• Process Chemistry Development: Used to establish scalable, efficient, and stereoselective routes for the commercial manufacture of high-value compounds.

Basic Information

Product Name	(S)-n-((S)-1-(tert-Butyldimethylsilyloxy)But-3-En-2-Yl)-2-Methylpropane-2-Sulfinamide
CAS No.	926660-07-3
Molecular Formula	C₁₄H₂₉NO₂SSi
Molecular Weight	303.53 g/mol
Synonyms	(S)-N-[(1S)-1-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-buten-2-yl]-2-methyl-2-propanesulfinamide; (S)-N-((S)-1-((tert-Butyldimethylsilyl)oxy)but-3-en-2-yl)-2-methylpropane-2-sulfinamide; tert-Butanesulfinamide, N-[(1S)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-buten-2-yl]-, (S)-; (S)-tert-Butanesulfinamide derivative; Chiral sulfinamide TBS ether; Chiral amine synthon; Asymmetric synthesis building block
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, which is critical for downstream synthesis. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (ee), and impurity profile is provided with every shipment. We operate under a GMP-compliant quality management system suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.