Description

n-(3-Oxohexadecanoyl)-L-Homoserine Lactone is a specialized N-acyl homoserine lactone (AHL) signaling molecule used in quorum sensing research. This compound is critical for studying bacterial cell-to-cell communication, biofilm formation, and virulence factor regulation in Gram-negative bacteria. It is an essential tool for researchers and developers in the fields of microbiology, pharmaceuticals, and agricultural science seeking to understand and potentially disrupt pathogenic bacterial processes.

Application

• Quorum Sensing Research: A key reagent for studying bacterial communication and gene regulation mechanisms.
• Anti-virulence Drug Discovery: Used in high-throughput screening to identify novel compounds that inhibit quorum sensing and reduce pathogenicity.
• Biofilm Studies: Essential for investigating the role of AHLs in the formation and maintenance of bacterial biofilms on surfaces.
• Agricultural Biotechnology: Applied in research to develop strategies for controlling plant pathogens by interfering with their signaling pathways.
• Microbial Ecology: Utilized to explore interspecies and intraspecies signaling within complex microbial communities.
• Academic & Industrial R&D: Serves as a standard and intermediate for synthetic and analytical work in life science laboratories.

Basic Information

Product Name	n-(3-Oxohexanecyl)-L-Homoserine Lactone
CAS No.	925448-37-9
Molecular Formula	C20H35NO4
Molecular Weight	353.50 g/mol
Synonyms	N-(3-Oxohexadecanoyl)homoserine lactone; 3-Oxo-C16-HSL; N-(3-Oxopalmitoyl)-L-homoserine lactone; N-3-Oxohexadecanoyl-L-homoserine lactone; C16-oxo-HSL; AHL C16:1 3-oxo; N-Acyl Homoserine Lactone C16 (3-oxo); Quorum Sensing Molecule C16-3-oxo-HSL
EINECS	Contact for details

Quality Control

Our n-(3-Oxohexadecanoyl)-L-Homoserine Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation and exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, ethanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.