Description

Ac-Val-Arg-Pro-Arg-Amc is a fluorogenic peptide substrate designed for the detection and study of specific protease activity. This compound is a critical tool for biochemical research and pharmaceutical development, enabling precise enzymatic assays. It is primarily utilized by researchers and quality control laboratories in the life sciences, biotechnology, and pharmaceutical industries for studying enzyme kinetics and screening potential therapeutic inhibitors.

Application

• Protease Activity Assays: Used as a selective substrate for monitoring the enzymatic activity of specific proteases in vitro.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for therapeutic development.
• Biochemical Research: Facilitates the study of enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial research settings.
• Diagnostic Development: Serves as a key component in the development of fluorometric diagnostic tests for detecting abnormal protease levels.
• Quality Control Testing: Used in biopharmaceutical manufacturing to monitor and validate the activity of enzyme-based products or processes.

Basic Information

Product Name	Ac-Val-Arg-Pro-Arg-Amc
CAS No.	919515-51-8
Molecular Formula	C31H49N11O7
Molecular Weight	663.80 g/mol
Synonyms	Ac-VRPR-Amc; Ac-Val-Arg-Pro-Arg-7-Amino-4-methylcoumarin; N-Acetyl-Valyl-Arginyl-Prolyl-Arginyl-7-Amino-4-methylcoumarin; Fluorogenic Substrate for Proteases; Protease Substrate VRPR-Amc; Thrombin Substrate Analog; Ac-VRPR-AMC; Ac-VRPR-AMC Hydrochloride (if applicable)
EINECS	Contact for details

Quality Control

Our Ac-Val-Arg-Pro-Arg-Amc is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.