Description

Methyl 11(R,S)-Hydroxy-14(S),15(S)-Epoxy-5(Z),8(Z),12(E)-Eicosatrienoate is a specialized synthetic eicosanoid derivative, a methyl ester of a complex epoxy-hydroxy fatty acid. This compound is of significant interest as a key intermediate and reference standard in advanced biochemical and pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers focusing on lipid signaling pathways, inflammation, and cardiovascular biology.

Application

• Biochemical Research Intermediate: Serves as a crucial synthetic precursor for the study of epoxy-eicosatrienoic acid (EET) analogs and related lipid mediators.
• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in drug discovery pipelines targeting cytochrome P450 pathways.
• Lipidomics & Metabolomics: An essential compound for profiling and quantifying oxylipins in biological samples to understand disease mechanisms.
• Cell Signaling Studies: Employed in vitro and ex vivo to investigate the role of specific eicosanoid regioisomers in cellular communication, inflammation, and vascular function.
• Enzyme Substrate/Inhibitor Research: Used to study the activity and inhibition of enzymes like soluble epoxide hydrolase (sEH).
• Academic & Institutional Research: Supports fundamental research in universities and government labs exploring the biochemistry of fatty acid epoxides.

Basic Information

Product Name	Methyl 11(R,S)-Hydroxy-14(S),15(S)-Epoxy-5(Z),8(Z),12(E)-Eicosatrienoate
CAS No.	911634-03-2
Molecular Formula	C21H34O4
Molecular Weight	350.49 g/mol
Synonyms	Methyl 11-Hydroxy-14,15-epoxy-5,8,12-eicosatrienoate; 11-Hydroxy-14,15-EET Methyl Ester; 14(S),15(S)-Epoxy-11(R,S)-hydroxy-5(Z),8(Z),12(E)-eicosatrienoic Acid Methyl Ester; Methyl 11-Hydroxy-14,15-epoxy-5Z,8Z,12E-eicosatrienoate; 11-OH-14,15-EET-Me; EET Methyl Ester Derivative; 11,14,15-Trihydroxy-5,8,12-eicosatrienoic Acid Methyl Ester (epoxy hydrate form)
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, isomeric purity, and chemical potency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data and specifications. Quality standards are designed to meet the rigorous demands of pharmaceutical research and analytical reference material applications.

Storage

Preserve in a tightly closed container under an inert atmosphere (e.g., argon or nitrogen), protected from light. For long-term stability, store at -20°C or below. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Isomeric Purity (Chiral HPLC)	≥ 90% (14(S),15(S)-epoxy isomer)
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.