Description

Epi-Sancycline Hydrochloride is a high-purity, semi-synthetic tetracycline derivative of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for investigating novel antibacterial agents and exploring structure-activity relationships. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel tetracycline-class antibiotics.
• Antibacterial Research: Used in microbiological and biochemical studies to investigate mechanisms of action against Gram-positive and Gram-negative bacteria.
• API Development: Acts as an Active Pharmaceutical Ingredient in pre-clinical and clinical formulation studies for new drug candidates.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aiming to modify the tetracycline core to enhance efficacy or reduce resistance.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Reagent: Utilized in life science research to study protein synthesis inhibition and bacterial ribosome function.

Basic Information

Product Name	Epi-Sancycline Hydrochloride
CAS No.	906364-48-5
Molecular Formula	C₂₂H₂₅ClN₂O₈
Molecular Weight	480.90 g/mol
Synonyms	Epi-Sancycline HCl; (4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; 4-Epi-Sancycline Hydrochloride; Sancycline Epimer Hydrochloride; 6-Methyl-4-epi-6-deoxy-6-demethyltetracycline Hydrochloride
EINECS	Contact for details

Quality Control

Our Epi-Sancycline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.