Description

Pe(22:1(13E)/22:1(13E)) is a high-purity synthetic phosphatidylethanolamine (PE) lipid featuring two erucic acid (22:1) chains with specific trans-13 double bond geometry. This compound is critical for advanced research and formulation development where lipid structure and purity directly influence experimental outcomes and product performance. It is primarily utilized by scientists and product developers in the pharmaceutical, biotechnology, and advanced materials sectors for constructing model membranes, developing lipid-based delivery systems, and studying membrane biophysics.

Application

• Lipid Nanoparticle (LNP) & Drug Delivery Research: A key component for formulating and optimizing non-viral vectors for mRNA, siRNA, and other nucleic acid therapeutics.
• Biomimetic Membrane Studies: Used to create defined model membranes (e.g., liposomes, supported lipid bilayers) for investigating protein-lipid interactions, membrane permeability, and cellular signaling.
• Pharmaceutical Excipient Development: Serves as a functional raw material in the development of liposomal drug products and other advanced lipid-based formulations.
• Biophysical & Biochemical Research: Essential tool for studying lipid raft formation, membrane fluidity, and the role of specific unsaturated PE lipids in cellular processes.
• Reference Standard & Analytical Applications: Employed as a high-purity standard in chromatography (HPLC, LC-MS) for lipidomic analysis and quality control of complex lipid mixtures.

Basic Information

Product Name	Pe(22:1(13E)/22:1(13E))
CAS No.	904304-57-0
Molecular Formula	C49H94NO8P
Molecular Weight	856.24 g/mol
Synonyms	1,2-Di(13E-docosenoyl)-sn-glycero-3-phosphoethanolamine; Dierucoyl Phosphatidylethanolamine; PE(44:2); 1,2-Dierucoyl-sn-glycero-3-phosphoethanolamine; (13E,13'E)-1,2-Bis(docos-13-enoyl)-sn-glycero-3-phosphoethanolamine; trans-13-Dierucoyl PE; Phosphatidylethanolamine (22:1(13E)/22:1(13E)); Erucoyl Phosphatidylethanolamine
EINECS	Contact for details

Quality Control

Every batch of Pe(22:1(13E)/22:1(13E)) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting requirements of research and pre-clinical development. Certificates of Analysis (COA) detailing specific results for purity (HPLC), identity (NMR, MS), and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.