Description

(3A,5B)-24-Oxo-24-[(2-Sulfoethyl)Amino]Cholan-3-Yl B-D-Glucopyranosiduronic Acid is a high-purity, synthetic bile acid derivative with a sulfated and glucuronidated structure, offering enhanced solubility and specific biological activity. This compound is critical for advanced research and development in pharmaceutical chemistry, particularly in the study of metabolic pathways and receptor interactions. It serves as a key intermediate or reference standard for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Acts as a critical reference standard or probe in studies of bile acid transporters, nuclear receptors (e.g., FXR, TGR5), and metabolic signaling pathways.
• Metabolite Standard: Employed in analytical laboratories as a certified reference material (CRM) for the quantification of bile acid metabolites in biological samples via LC-MS or HPLC.
• Drug Discovery: Serves as a building block or a lead compound for developing new drugs with improved pharmacokinetic profiles.
• Enzyme Substrate/Inhibitor Studies: Utilized in enzymatic assays to investigate the activity of sulfotransferases, glucuronosyltransferases, or other modifying enzymes.

Basic Information

Product Name	(3A,5B)-24-Oxo-24-[(2-Sulfoethyl)Amino]Cholan-3-Yl B-D-Glucopyranosiduronic Acid
CAS No.	99794-82-8
Molecular Formula	C32H52N2O12S
Molecular Weight	688.83 g/mol
Synonyms	24-Oxo-24-[(2-sulfoethyl)amino]cholan-3-yl β-D-glucopyranosiduronic acid; Tauro-3β-glucosiduronic acid-7α,12α-dihydroxy-5β-cholan-24-oic acid derivative; 3β-[(β-D-Glucopyranosiduronic acid)]-24-oxo-24-[(2-sulfoethyl)amino]-5β-cholane; Sulfated glucuronide bile acid analog; N-(2-Sulfoethyl)-3β-glucosiduronyl-5β-cholan-24-amide 24-one
EINECS	Contact for details

Quality Control

Our production of (3A,5B)-24-Oxo-24-[(2-Sulfoethyl)Amino]Cholan-3-Yl B-D-Glucopyranosiduronic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.