Description

6H-Purin-6-One, 2-Amino-1,9-Dihydro-9-(4-Hydroxy-3-(Hydroxymethyl)-2-Butenyl)- is a high-purity purine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation nucleotide analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and signaling pathways.
• Nucleoside/Nucleotide Chemistry: Serves as a core scaffold for the modification and creation of novel nucleoside derivatives with potential therapeutic activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Drug Development: Utilized in early-stage discovery for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Item	Detail
Product Name	6H-Purin-6-One, 2-Amino-1,9-Dihydro-9-(4-Hydroxy-3-(Hydroxymethyl)-2-Butenyl)-
CAS No.	99776-28-0
Molecular Formula	C10H13N5O3
Molecular Weight	251.24 g/mol
Synonyms	9-[(4-Hydroxy-3-(hydroxymethyl)-2-buten-1-yl)]guanine; H2G; 2-Amino-9-[(4-hydroxy-3-(hydroxymethyl)-2-buten-1-yl)]-1,9-dihydro-6H-purin-6-one; (E)-9-(4-Hydroxy-3-hydroxymethylbut-2-enyl)guanine; 2-Amino-9-(4-hydroxy-3-hydroxymethylbut-2-enyl)purin-6-one; Guanine, 9-[(4-hydroxy-3-(hydroxymethyl)-2-buten-1-yl)]-
EINECS	Contact for details

Quality Control

Our 6H-Purin-6-One, 2-Amino-1,9-Dihydro-9-(4-Hydroxy-3-(Hydroxymethyl)-2-Butenyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support development and commercial projects requiring material that meets stringent research-grade or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.