Description

Ondansetron CAS NO 99614-60-5 is a highly selective serotonin 5-HT₃ receptor antagonist. This compound is critically important for its potent antiemetic properties, effectively preventing nausea and vomiting. It is an essential active pharmaceutical ingredient (API) primarily needed by pharmaceutical manufacturers for the production of injectable solutions, oral tablets, and orally disintegrating films used in oncology, post-operative care, and other clinical settings.

Application

• Primary use as the Active Pharmaceutical Ingredient (API) in antiemetic medications.
• Formulation of injectable solutions for hospital and clinical use, particularly in chemotherapy-induced nausea and vomiting (CINV).
• Manufacturing of oral dosage forms, including standard tablets and orally disintegrating tablets (ODTs).
• Production of oral soluble films for rapid-onset therapy.
• Research and development of new drug delivery systems and combination therapies.
• Reference standard in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Ondansetron
CAS No.	99614-60-5
Molecular Formula	C18H19N3O
Molecular Weight	293.37 g/mol
Synonyms	1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one; GR 38032F; Zofran (trade name); SN 307; (±)-Ondansetron; NSC-326231; UNII-4AF302ESOS
EINECS	Contact for details

Quality Control

Our Ondansetron is manufactured under strict quality management systems. It is tested to meet or exceed relevant pharmacopeial standards such as USP and EP. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.