Description

Thiethylperazine is a phenothiazine derivative with potent antiemetic and antipsychotic properties. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of medications to control severe nausea and vomiting. It is primarily required by pharmaceutical manufacturers and research institutions developing treatments for conditions such as vertigo, migraine, and chemotherapy-induced nausea. Thiethylperazine CAS NO 1420-55-9 is supplied as a high-purity material suitable for GMP manufacturing processes.

Application

• Pharmaceutical API: Primary use as the active ingredient in antiemetic and antipsychotic drug formulations.
• Neurological Research: Used in preclinical studies to investigate dopaminergic and serotonergic pathways.
• Vestibular Disorder Treatment: Key component in medications for Ménière's disease and other vertigo-related conditions.
• Oncology Supportive Care: Formulated to manage nausea and vomiting associated with chemotherapy and radiation therapy.
• Migraine Management: Incorporated into therapeutic regimens for the relief of migraine-associated nausea.
• Reference Standard: Serves as a certified reference material for quality control and analytical testing in laboratories.

Basic Information

Product Name	Thiethylperazine
CAS No.	1420-55-9
Molecular Formula	C22H29N3S2
Molecular Weight	399.62 g/mol
Synonyms	Torecan; Thiethylperazine Maleate; Thiethylperazine Dimaleate; 2-Ethyl-3-(10H-phenothiazin-10-yl)propyl]piperazine; EINECS 215-824-8; NSC-130046; SQ-11201; Toresten
EINECS	215-824-8

Quality Control

Our Thiethylperazine is manufactured and tested under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with comprehensive testing including identification, assay, and impurity profile. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.