Description

Scopolamine Hydrobromide Trihydrate is a high-purity, crystalline alkaloid salt widely recognized for its potent anticholinergic properties. This compound is essential for precise pharmaceutical research and manufacturing, where consistent quality and reliable supply are paramount. It serves as a critical active pharmaceutical ingredient (API) and intermediate for developers and manufacturers in the pharmaceutical, biotechnology, and advanced research sectors.

Application

• Pharmaceutical API: Primary active ingredient in formulations for motion sickness prevention, postoperative nausea and vomiting (PONV) control, and as an adjunct in anesthesia.
• Transdermal Therapeutic Systems: Key component in medicated patches designed for controlled, long-term delivery of scopolamine.
• Ophthalmic Solutions: Used in diagnostic procedures and treatments as a mydriatic (pupil dilator) and cycloplegic (paralyzes accommodation).
• Neurological Research: Vital tool in preclinical studies investigating cholinergic pathways, smooth muscle physiology, and central nervous system (CNS) functions.
• Analytical Reference Standard: Serves as a certified standard for quality control (QC) and assay development in analytical laboratories.
• Veterinary Medicine: Employed in veterinary practices for its sedative and antiemetic effects in certain animal species.

Basic Information

Product Name	Scopolamine Hydrobromide Trihydrate
CAS No.	6533-68-2
Molecular Formula	C17H21NO4 • HBr • 3H2O
Molecular Weight	438.32 g/mol
Synonyms	Hyoscine Hydrobromide Trihydrate; (-)-Scopolamine Hydrobromide Trihydrate; Scopolamine HBr Trihydrate; 6β,7β-Epoxy-3α-tropanyl S-(-)-tropate Hydrobromide Trihydrate; L-Hyoscine Hydrobromide Trihydrate; Transderm Scōp API; Buscopan (related compound); EINECS 229-437-0
EINECS	229-437-0

Quality Control

Our Scopolamine Hydrobromide Trihydrate is manufactured under strict quality management systems. Each batch is tested to meet stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards (e.g., USP, EP) where applicable. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	10.0% - 13.0%
Specific Rotation	-24° to -28° (c = 5 in H2O)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.