Description

Ondansetron CAS NO 116002-70-1 is a highly selective serotonin 5-HT₃ receptor antagonist, a critical active pharmaceutical ingredient (API) in modern therapeutics. Its primary value lies in its potent efficacy for preventing nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative conditions. This makes it an essential raw material for pharmaceutical manufacturers developing antiemetic formulations, including injectables, oral tablets, and orally disintegrating films. We supply high-purity Ondansetron to support the global pharmaceutical supply chain with reliable, quality-assured material.

Application

• Primary API for the manufacture of prescription antiemetic medications.
• Key ingredient in injectable formulations used in hospital and clinical oncology settings.
• Core component in oral solid dosage forms such as tablets and orally disintegrating tablets (ODTs).
• Used in the research and development of new drug delivery systems and combination therapies.
• Reference standard in analytical laboratories for quality control and method validation.
• Starting material for the synthesis of novel derivatives in pharmaceutical research.

Basic Information

Product Name	Ondansetron
CAS No.	116002-70-1
Molecular Formula	C18H19N3O
Molecular Weight	293.36 g/mol
Synonyms	Ondansetron Hydrochloride Dihydrate (common salt form); GR 38032F; Zofran® (brand name); 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one; (±)-1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one; 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-
EINECS	Contact for details

Quality Control

Our Ondansetron is manufactured under strict quality management systems. It is tested to meet stringent specifications for pharmaceutical use, with compliance to relevant pharmacopeial standards such as USP and EP. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The material is hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Microbial Limits	Conforms to EP/USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.