Description

(1B,3A,5B,7A)-1,3,7-Trihydroxy-Cholan-24-Oic Acid CAS NO 99598-04-6 is a high-purity, multi-hydroxylated bile acid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are critical for developing targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel metabolic and liver-targeted drugs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel bile acid analogs and hepatoprotective agents.
• Metabolic Research: Used as a reference standard or active probe in studies of bile acid metabolism, liver function, and related pathways.
• Drug Discovery: Serves as a scaffold for medicinal chemistry programs targeting nuclear receptors like FXR (Farnesoid X receptor).
• Biochemical Reagent: Employed in enzymatic studies and as a substrate for investigating specific biochemical transformations.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related pharmaceutical products.

Basic Information

Product Name	(1B,3A,5B,7A)-1,3,7-Trihydroxy-Cholan-24-Oic Acid
CAS No.	99598-04-6
Molecular Formula	C₂₄H₄₀O₆
Molecular Weight	424.57 g/mol
Synonyms	1,3,7-Trihydroxycholan-24-oic Acid; 1β,3α,7α-Trihydroxy-5β-cholan-24-oic Acid; 3α,7α,1β-Trihydroxy-5β-cholan-24-oic Acid; Trihydroxy Cholanic Acid; 1β,3α,7α-Trihydroxy-5β-cholanoic Acid; 5β-Cholan-24-oic acid, 1β,3α,7α-trihydroxy-; 99598-04-6
EINECS	Contact for details

Quality Control

Our (1B,3A,5B,7A)-1,3,7-Trihydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.