Description

1-Oleoyl-2-(7-(4-Nitrobenzo-2-Oxa-1,3-Diazole))-6-Aminocaproylphosphatidylcholine is a high-purity, fluorescently labeled phospholipid derivative, specifically engineered for advanced research and diagnostic applications. This compound is critical for studying membrane dynamics, lipid trafficking, and cellular signaling pathways due to its specific fluorescent properties. It is primarily utilized by researchers and developers in the fields of biochemistry, cell biology, and diagnostic assay development, where precise molecular tagging is required.

Application

• Fluorescent Cell Membrane Probes: Used as a vital tool for real-time visualization and tracking of lipid distribution and movement within cellular membranes.
• Lipidomics Research: Serves as a standard or tracer in mass spectrometry and chromatography-based studies to understand lipid metabolism and interactions.
• Liposome and Drug Delivery System Development: Incorporated into liposomal formulations to study encapsulation efficiency, stability, and cellular uptake mechanisms.
• Diagnostic Assay Development: Employed in the creation of sensitive fluorescence-based assays for detecting enzymes like phospholipases or for biomarker studies.
• Model Membrane Studies: Used in artificial bilayer systems (e.g., supported lipid bilayers, vesicles) to investigate phase behavior, fusion, and protein-lipid interactions.
• Apoptosis and Cell Signaling Research: Acts as a probe to monitor changes in membrane phospholipid asymmetry and related signaling events during cellular processes.

Basic Information

Product Name	1-Oleoyl-2-(7-(4-Nitrobenzo-2-Oxa-1,3-Diazole))-6-Aminocaproylphosphatidylcholine
CAS No.	99566-32-2
Molecular Formula	C55H92N5O12P
Molecular Weight	1046.33 g/mol
Synonyms	NBD-C6-HPC; 1-Oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine; NBD C6 Phosphatidylcholine; Fluorescent Phosphatidylcholine NBD; NBD-labeled PC; 2-(NBD-amino)caproylphosphatidylcholine; 1-Oleoyl-2-NBD-HPC; NBD C6-HPC
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-2-(7-(4-Nitrobenzo-2-Oxa-1,3-Diazole))-6-Aminocaproylphosphatidylcholine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and fluorescent integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is both light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere such as argon or nitrogen to prevent oxidation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, methanol, DMSO
Fluorescence Properties	Excitation ~465 nm, Emission ~535 nm (in methanol)
Water Content (KF)	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.