Description

(S)-1,4-Ditosyl-2-Butanol CAS NO 99520-82-8 is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its enantiomerically pure structure and dual tosyl protecting groups make it a versatile precursor for constructing complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and specialty chemicals requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis Research: Used as a starting material or ligand precursor in the development and study of new catalytic systems.
• Natural Product Synthesis: Serves as a building block for the total synthesis of complex natural products with defined stereocenters.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials where optical purity is critical.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and stereoselective transformations.

Basic Information

Product Name	(S)-1,4-Ditosyl-2-Butanol
CAS No.	99520-82-8
Molecular Formula	C18H22O5S2
Molecular Weight	382.49 g/mol
Synonyms	(S)-2-Butanol, 1,4-bis(4-methylbenzenesulfonate); (S)-1,4-Bis(tosyloxy)-2-butanol; (S)-1,4-Di-O-tosyl-2-butanol; (2S)-1,4-Bis[(4-methylphenyl)sulfonyl]oxybutan-2-ol; (S)-1,4-Ditosyloxy-2-butanol; (S)-DTB; (S)-1,4-Di-p-toluenesulfonyl-2-butanol
EINECS	Contact for details

Quality Control

Our (S)-1,4-Ditosyl-2-Butanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and purity assessment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.