Description

n-Acetylmuramyl-Alanyl-Isoglutamine-Alanyl-Cholesterol is a sophisticated synthetic lipopeptide conjugate, combining a muramyl dipeptide (MDP) derivative with a cholesterol moiety. This unique structure is designed to enhance immunomodulatory activity and cellular delivery, making it a valuable tool in advanced pharmaceutical research and development. It is primarily utilized by researchers and developers in the fields of vaccine adjuvants, immunotherapies, and novel drug delivery systems, where precise molecular engineering is critical for efficacy.

Application

• Vaccine Adjuvant Research: Investigated for its potential to enhance and modulate immune responses in next-generation vaccine formulations.
• Immunotherapy Development: Serves as a key component in the design of novel immunomodulatory agents targeting specific immune pathways.
• Drug Delivery Systems: Utilized as a functional building block in liposomal or nanoparticle-based delivery platforms to improve cellular uptake and targeting.
• Biochemical Research: Acts as a reference standard or active compound in studies of innate immunity, particularly involving NOD2 receptor signaling.
• Pharmaceutical Intermediates: Used in the synthesis of more complex immunostimulatory compounds and conjugates.

Basic Information

Product Name	n-Acetylmuramyl-Alanyl-Isoglutamine-Alanyl-Cholesterol
CAS No.	99518-28-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MDP-Cholesterol Conjugate; Muramyl Dipeptide-Cholesterol; Lipo-MDP; Cholesterol-Muramyl Dipeptide; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-L-alanyl Cholesterol; Adjuvant Peptide-Cholesterol Conjugate; Immunostimulant Lipopeptide
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-Alanyl-Isoglutamine-Alanyl-Cholesterol is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support its use in pharmaceutical development. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to minimize moisture ingress. For extended storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.