Description

5'-Trimethylammonium-Delta(8)-Tetrahydrocannabinol is a quaternary ammonium salt derivative of the cannabinoid δ-8-THC, designed for enhanced stability and specific biological activity. This compound is of significant interest for advanced pharmaceutical research and the development of novel therapeutic agents targeting the endocannabinoid system. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in neuroscience, pharmacology, and medicinal chemistry.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantification and identification of cannabinoid derivatives in analytical methods such as HPLC and LC-MS.
• Medicinal Chemistry Research: Used as a key intermediate or active pharmacophore in the synthesis and development of new cannabinoid-based therapeutics.
• Neuroscience Studies: Employed in preclinical research to investigate the structure-activity relationships (SAR) and pharmacological profiles of modified cannabinoids.
• Metabolite Analysis: Acts as a critical standard for the detection and study of cannabinoid metabolites in forensic and clinical toxicology.
• Biochemical Assay Development: Utilized in the creation of high-throughput screening assays to discover new modulators of cannabinoid receptors.
• Process Development & Scale-up: Supports process chemistry efforts for the scalable synthesis of specialized cannabinoid compounds under GMP conditions.

Basic Information

Product Name	5'-Trimethylammonium-Delta(8)-Tetrahydrocannabinol
CAS No.	99469-31-5
Molecular Formula	C24H39NO2+ (typically associated with an anion, e.g., iodide)
Molecular Weight	~373.58 g/mol (for cation, varies with counter-ion)
Synonyms	5'-Trimethylammonium-δ8-THC; δ8-THC Trimethylammonium Salt; (6aR,10aR)-6,6,9-Trimethyl-3-(2-(trimethylammonio)ethyl)-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol; N,N,N-Trimethyl-2-((1R,6R)-3-hydroxy-6-isopropenyl-6-methyl-9-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-yl)ethan-1-aminium; Cannabinoid QA Salt
EINECS	Contact for details

Quality Control

Our 5'-Trimethylammonium-Delta(8)-Tetrahydrocannabinol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.