Description

4-Methylumbelliferyl 2-Acetamido-2-Deoxy-β-D-Galactopyranoside 6-Sulfate is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific glycosidase enzyme activity. This compound matters as a critical research tool for studying carbohydrate metabolism and related enzymatic pathways in biochemistry and molecular biology. It is primarily needed by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on enzymology, glycobiology, and the development of high-throughput screening assays.

Application

• Enzymatic Substrate for Research: A fluorogenic substrate for the specific detection and kinetic study of β-N-acetylhexosaminidases and related sulfatases.
• Diagnostic Assay Development: Used in the formulation of diagnostic kits for the detection of lysosomal storage disorders, such as certain mucopolysaccharidoses, where specific enzyme deficiencies occur.
• High-Throughput Screening (HTS): Employed in pharmaceutical discovery for screening compound libraries against specific glycosidase targets.
• Biochemical Research: Essential for in vitro studies of enzyme mechanisms, inhibition, and characterization within the field of glycobiology.
• Cell-Based Assays: Utilized to monitor intracellular enzyme activity in live or fixed cells, providing insights into cellular metabolism and disease states.
• Quality Control in Biologics: Acts as a reagent in quality control tests for enzyme preparations and recombinant proteins.

Basic Information

Product Name	4-Methylumbelliferyl 2-Acetamido-2-Deoxy-β-D-Galactopyranoside 6-Sulfate
CAS No.	99389-63-6
Molecular Formula	C₁₈H₂₁NO₁₂S
Molecular Weight	475.42 g/mol
Synonyms	4-MU-β-D-GalNAc-6S; 4-Methylumbelliferyl N-acetyl-β-D-galactosaminide-6-sulfate; 4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-galactopyranoside-6-sulfate; 4-MU-β-GalNAc-6-sulfate; Fluorogenic β-N-acetylgalactosaminidase-6-sulfate substrate; 4-Methylumbelliferyl β-D-GalNAc-6-sulfate; 6-Sulfo-2-acetamido-2-deoxy-β-D-galactopyranosyl 4-methylumbelliferone
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl 2-Acetamido-2-Deoxy-β-D-Galactopyranoside 6-Sulfate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Optical Rotation	Contact for details
Fluorogenic Activity	Functional in standard assay systems

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.